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Article type: Research Article
Authors: Xiong, Qia; b | Song, Xianqia; b | Yang, Menga; b; c | Zhou, Lijuna; b | Li, Zhea; b | Zhu, Xinhuia; b | Zhi, Lia; b;
Affiliations: [a] College of Electrical Engineering & New Energy, China Three Gorges University, Yichang, China | [b] Hubei Provincial Engineering Technology Research Center for Power Transmission Line, China Three Gorges University, Yichang, China | [c] Suixi Power Supply Company, State Grid Anhui Electric Power Co. Ltd., Huaibei, China
Correspondence: [*] Corresponding author: Li Zhi, College of Electrical Engineering & New Energy, China Three Gorges University, Yichang 443002, China; and Hubei Provincial Engineering Technology Research Center for Power Transmission Line, China Three Gorges University, Yichang 443002, China. E-mail: zhili@ctgu.edu.cn
Abstract: Magnetic targeted drug delivery systems can improve drug utilization and reduce drug side effects. There are still many difficulties to be overcome in clinical practice. The main problems include providing large enough magnetic capture particles to concentrate drug-loaded magnetic micro-nanoparticles (MNPs) to the lesion site. The existing research focuses on the development of targeted carriers, and the magnet device has not formed a mature research system. Based on the recent development of magnet devices in recent years, this paper proposes the research direction of potential magnet devices. From the dynamic behavior of the particles under the magnetic field, the magnetic system and the mathematical model design direction of the optimized magnet are developed. This article describes the obstacles encountered in drug targeting in the study of magnet devices and summarizes the potential development of future magnet devices.
Keywords: Magnetic targeted drug delivery system, magnet device, targeted behavior
DOI: 10.3233/JAE-210021
Journal: International Journal of Applied Electromagnetics and Mechanics, vol. 67, no. 3, pp. 261-277, 2021
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