Clinical Hemorheology and Microcirculation - Volume 1, issue 5-6
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Price: EUR 185.00
Impact Factor 2019: 1.642
Clinical Hemorheology and Microcirculation, a peer-reviewed international scientific journal, serves as an aid to understanding the flow properties of blood and the relationship to normal and abnormal physiology. The rapidly expanding science of hemorheology concerns blood, its components and the blood vessels with which blood interacts. It includes perihemorheology, i.e., the rheology of fluid and structures in the perivascular and interstitial spaces as well as the lymphatic system. The clinical aspects include pathogenesis, symptomatology and diagnostic methods, and the fields of prophylaxis and therapy in all branches of medicine and surgery, pharmacology and drug research.
The endeavour of the Editors-in-Chief and publishers of
Clinical Hemorheology and Microcirculation is to bring together contributions from those working in various fields related to blood flow all over the world. The editors of
Clinical Hemorheology and Microcirculation are from those countries in Europe, Asia, Australia and America where appreciable work in clinical hemorheology and microcirculation is being carried out. Each editor takes responsibility to decide on the acceptance of a manuscript. He is required to have the manuscript appraised by two referees and may be one of them himself. The executive editorial office, to which the manuscripts have been submitted, is responsible for rapid handling of the reviewing process.
Clinical Hemorheology and Microcirculation accepts original papers, brief communications, mini-reports and letters to the Editors-in-Chief. Review articles, providing general views and new insights into related subjects, are regularly invited by the Editors-in-Chief. Proceedings of international and national conferences on clinical hemorheology (in original form or as abstracts) complete the range of editorial features.
The following professionals and institutions will benefit most from subscribing to
Clinical Hemorheology and Microcirculation: medical practitioners in all fields including hematology, cardiology, geriatrics, angiology, surgery, obstetrics and gynecology, ophthalmology, otology, and neurology. Pharmacologists, clinical laboratories, blood transfusion centres, manufacturing firms producing diagnostic instruments, and the pharmaceutical industry will also benefit.
Important new topics will increasingly claim more pages of
Clinical Hemorheology and Microcirculation: the role of hemorheological and microcirculatory disturbances for epidemiology and prognosis, in particular regarding cardiovascular disorders, as well as its significance in the field of geriatrics. Authors and readers are invited to contact the editors for specific information or to make suggestions.
Abstract: The resistance to blood flow is equal to the product of vascular hindrance and blood viscosity, which is a function of hematocrit, plasma viscosity, red cell aggregation and red cell deformability. These hemorheo1ogical components can be assessed by using a systematic approach. Data obtained from patients with hematological disorders (polycythemia, multiple myeloma, sialic acid deficiency and sickle cell disease) indicate that abnormalities in one rheological component may be associated with either coexisting abnormalities or compensatory changes in other components. Correlation with in vivo hemodynamic functions has shown that hemorheological abnormalities may affect flow resistance and oxygen transport and that…a normal cardiovascular system has the capacity to compensate for these disturbances, e.g. , by vasodilation. Hemorheological abnormalities are also found to exist in cardiovascular diseases (e.g. , myocardial infarction, hypertension and peripheral vascular disease). Although these abnormalities are milder than those found in hematological disorders, their pathophysiological significance is enhanced by the mutual amplification, rather than compensation, of the disturbances in hemorheological and cardiovascular functions. Improvement of blood rheology is a promising approach in the treatment of circulatory diseases.