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Price: EUR 185.00Authors: Bernard, Claude
Article Type: Editorial
DOI: 10.3233/CH-1981-1101
Citation: Clinical Hemorheology and Microcirculation, vol. 1, no. 1, pp. 1-2, 1981
Authors: Copley, Alfred L.
Article Type: Editorial
DOI: 10.3233/CH-1981-1102
Citation: Clinical Hemorheology and Microcirculation, vol. 1, no. 1, pp. 3-8, 1981
Authors: Copley, Alfred L.
Article Type: Introduction
DOI: 10.3233/CH-1981-1103
Citation: Clinical Hemorheology and Microcirculation, vol. 1, no. 1, pp. 9-72, 1981
Authors: Kaul, Dhananjaya K. | Baez, Silvio | Nagel, Ronald L.
Article Type: Research Article
Abstract: Experiments were carried out to determine flow properties of oxygenated normal and abnormal blood (HbAA, HbAS, HbSS, HbSC, HbAC, HbCC and rat) using isolated artificially perfused rat mesoappendix microvasculature. Changes in arterial perfusion pressure (Ppa) and venous outflow (Fv) were recorded after the infusion of blood, and peripheral resistance unit (PRU) was calculated. In a series of experiments, pressure-flow recovery time (Tpf) was determined, and microphotography was done in selected experiments. Viscometry was carried out at a shear rate of 230 sec−1 In the perfused mesoappendix, HbSS and HbSC blood resulted in higher PRU as well as increase in …Tpf when compared to those for HbCC blood, though the latter was more viscous. Evidence is presented regarding the trapping and fragmentation of the irreversibly sickled cells (ISC) in microvasculature. The possible role of certain cellular factors favoring the apparently normal microcirculatory behavior of HbCC blood is analyzed. Show more
Keywords: Microcirculation, Viscosity, Erythrocytes, Hemoglobinopathies, Hematocrit (Hct), Hemodynamic
DOI: 10.3233/CH-1981-1104
Citation: Clinical Hemorheology and Microcirculation, vol. 1, no. 1, pp. 73-86, 1981
Authors: Seaman, G.V.F. | Corry, W.D. | Blume, Philip | Jackson, Lavelle
Article Type: Research Article
Abstract: Analysis of extensive data in the literature plus a survey of our own limited clinical results indicate that changes in plasma viscosity (PV) primarily reflect alterations in the concentration of plasma macromolecules. The erythrocyte sedimentation rate (ESR) and zeta sedimentation ratio (ZSR) tests mainly detect the presence of macromolecules in the plasma which produce rouleaux or aggregates. The ESR test as presently used is, however, more prone to produce data supporting erroneous conclusion than the ZSR. It currently seems reasonable to eliminate ESR measurements and use only PV and ZSR measurements in clinical evaluations.
Keywords: aggregation, erythrocyte, plasma, serum, sedimentation, viscosity
DOI: 10.3233/CH-1981-1105
Citation: Clinical Hemorheology and Microcirculation, vol. 1, no. 1, pp. 87-98, 1981
Authors: Ehrly, Albrecht M. | Landgraf, Helmut
Article Type: Research Article
Abstract: The flow properties of blood were measured with various methods (rheologic analysis battery) before and after the infusion of 500 ml of a) 10 % low molecular weight dextran solution and b) of a 0,9 % sodium chloride solution in healthy volunteers. LMWD decreases blood viscosity, but increases plasma viscosity. Red cell filtration is decreased. There is no specific disaggregating effect of LMWD. After infusion of saline there is a transient decrease in blood and plasma viscosity, and an increase in filtration rate. No specific reduction in red cell aggregation could be found.
Keywords: Hemorheology, Low molecular weight dextran, Physiological saline
DOI: 10.3233/CH-1981-1106
Citation: Clinical Hemorheology and Microcirculation, vol. 1, no. 1, pp. 99-109, 1981
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