Affiliations: [a] Department of Speech and Hearing Disorders and Sciences, National Taipei University of Nursing and Health Sciences and Department of Otorhinolaryngology, Mackay Memorial Hospital, Taipei, Taiwan | [b] Department of Otolaryngology-Head and Neck Surgery, Division of Otology, Taipei Veterans General Hospital, Taipei, Taiwan | [c] Department of Otorhinolaryngology, Faculty of Medicine, and Institute of Brain Science, School of Medicine, National Yang-Ming University, Taipei, Taiwan | [d] Department of Otorhinolaryngology, Renai Branch, Taipei City Hospital, Taipei, Taiwan
Correspondence:
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Corresponding author: Guo-She Lee, MD., PhD., Department of Otolaryngology, Faculty of Medicine, School of Medicine, National Yang-Ming University. No. 155, Sec. 2, Linong St., Beitou District, Taipei City 112 Taiwan. E-mail: guosheli@ms12.hinet.net; gslee@ym.edu.tw
Note: [1] Miss Huei-Jun Wu contributed as a co-first author in this work.
Abstract: The responses of ocular vestibular evoked myogenic potential (oVEMP) vary significantly with the type and setting of the stimuli. This work was to investigate the effects of different ramp time and plateau time on oVEMP latency and amplitude. Twenty-two healthy volunteers aged from 20 years to 39 years were enrolled. The oVEMPs were acquired with the eyes upwards-gaze 30 degree above the head, and the sound stimuli included 0.1-ms click, and 500-Hz short tone burst (STB) of rise-plateau-fall time of 0.5-2-0.5 ms, 0.5-4-0.5 ms, 2-2-2 ms, and 2-4-2 ms. The response rate of click oVEMP (66%) was lower than STB oVEMP (100%). The click oVEMP amplitude was significantly smaller (p < 0.01, one-way ANOVA and post-hoc Scheffe procedure). The latency n1 increased by 1.4 ms as the rise/fall time shifted from 0.5 ms to 2 ms for STB stimuli. However, the latency and amplitude did not show significant difference between the STB stimuli with different plateau times. The lower amplitude and response rate for click oVEMP were associated with its lower mechanical energy of click, especially the energy from 500 to 1000 Hz.
Keywords: Vestibular evoked myogenic potential, ocular, click, short tone burst, plateau time, ramp time
