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Clinical Hemorheology and Microcirculation - Volume 88, issue 4

Purchase individual online access for 1 year to this journal.

Price: EUR 185.00
Impact Factor 2024: 2.1

Clinical Hemorheology and Microcirculation, a peer-reviewed international scientific journal, serves as an aid to understanding the flow properties of blood and the relationship to normal and abnormal physiology. The rapidly expanding science of hemorheology concerns blood, its components and the blood vessels with which blood interacts. It includes perihemorheology, i.e., the rheology of fluid and structures in the perivascular and interstitial spaces as well as the lymphatic system. The clinical aspects include pathogenesis, symptomatology and diagnostic methods, and the fields of prophylaxis and therapy in all branches of medicine and surgery, pharmacology and drug research.

The endeavour of the Editors-in-Chief and publishers of Clinical Hemorheology and Microcirculation is to bring together contributions from those working in various fields related to blood flow all over the world. The editors of Clinical Hemorheology and Microcirculation are from those countries in Europe, Asia, Australia and America where appreciable work in clinical hemorheology and microcirculation is being carried out. Each editor takes responsibility to decide on the acceptance of a manuscript. He is required to have the manuscript appraised by two referees and may be one of them himself. The executive editorial office, to which the manuscripts have been submitted, is responsible for rapid handling of the reviewing process.

Clinical Hemorheology and Microcirculation accepts original papers, brief communications, mini-reports and letters to the Editors-in-Chief. Review articles, providing general views and new insights into related subjects, are regularly invited by the Editors-in-Chief. Proceedings of international and national conferences on clinical hemorheology (in original form or as abstracts) complete the range of editorial features.

The following professionals and institutions will benefit most from subscribing to Clinical Hemorheology and Microcirculation: medical practitioners in all fields including hematology, cardiology, geriatrics, angiology, surgery, obstetrics and gynecology, ophthalmology, otology, and neurology. Pharmacologists, clinical laboratories, blood transfusion centres, manufacturing firms producing diagnostic instruments, and the pharmaceutical industry will also benefit.

Important new topics will increasingly claim more pages of Clinical Hemorheology and Microcirculation: the role of hemorheological and microcirculatory disturbances for epidemiology and prognosis, in particular regarding cardiovascular disorders, as well as its significance in the field of geriatrics. Authors and readers are invited to contact the editors for specific information or to make suggestions.

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Encapsulated papillary carcinoma of breast: Comparative study of multimodal ultrasound manifestations and pathological features

Authors: Wu, Zehong | Li, Huajuan | Chen, Zihao | Zhou, Honglian | Liang, Xin | Huang, Xing | Wang, Jiexin | Chen, Ting | Xu, Xiaohong | Yang, Yuping

Article Type: Research Article

Abstract: OBJECTIVE: To investigate the conventional ultrasound (US), contrast-enhanced ultrasound (CEUS) manifestations and the corresponding histopathological characteristics of patients diagnosed with breast encapsulated papillary carcinoma (EPC) and to explore the value of CEUS in diagnosis of EPC. METHODS: The clinical, pathological, US, and CEUS features of 16 patients (17 lesions) with EPC confirmed by postoperative histopathology were retrospectively analyzed. RESULTS: EPC was prevalent in the postmenopausal women. The majority of conventional US images of EPC showed complex cystic and solid masses with circumscribed margins (70.6%), enhanced posterior echo (94.1%), no sonographic calcification (88.2%), rich blood flow in … Show more

Keywords: Breast tumor, encapsulated papillary carcinoma of the breast, ultrasound features, contrast-enhanced ultrasound, pathology

DOI: 10.3233/CH-242263

Citation: Clinical Hemorheology and Microcirculation, vol. 88, no. 4, pp. 537-549, 2024

Price: EUR 27.50

Rosuvastatin inhibit ox-LDL-induced platelet activation by the p38/MAPK pathway

Authors: Liu, Jinming | Jiao, Wei | Li, Fang | Xie, Yanan | Meng, Mingjie | Hao, Jie

Article Type: Research Article

Abstract: OBJECTIVE: This study intends to explore the effects of Rosuvastatin on ox-LDL induced platelet activation and its molecular mechanism. METHODS: Platelet aggregation rate was detected by aggregometer. ELISA kit was used to detect the levels of cAMP. Immunofluorescence staining was used to detect the platelet adhesion. The expression levels of platelet surface markers CD62p and PAC-1 were detected by flow cytometry. The protein levels of p-p38, p-IKKa and p-IKKB in platelets were detected by western blot. RESULTS: We found that rosuvastatin significantly inhibited platelet aggregation and increased the level of cAMP in a dose-dependent manner. Immunofluorescence … Show more

Keywords: Rosuvastatin, platelet, aggregation, adhesion, p38/MAPK

DOI: 10.3233/CH-242359

Citation: Clinical Hemorheology and Microcirculation, vol. 88, no. 4, pp. 551-560, 2024

Price: EUR 27.50
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