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Biorheology is an international interdisciplinary journal that publishes research on the deformation and flow properties of biological systems or materials. It is the aim of the editors and publishers of
Biorheology to bring together contributions from those working in various fields of biorheological research from all over the world. A diverse editorial board with broad international representation provides guidance and expertise in wide-ranging applications of rheological methods to biological systems and materials.
The aim of biorheological research is to determine and characterize the dynamics of physiological processes at all levels of organization. Manuscripts should report original theoretical and/or experimental research promoting the scientific and technological advances in a broad field that ranges from the rheology of macromolecules and macromolecular arrays to cell, tissue and organ rheology. In all these areas, the interrelationships of rheological properties of the systems or materials investigated and their structural and functional aspects are stressed.
The scope of papers solicited by
Biorheology extends to systems at different levels of organization that have never been studied before, or, if studied previously, have either never been analyzed in terms of their rheological properties or have not been studied from the point of view of the rheological matching between their structural and functional properties. This biorheological approach applies in particular to molecular studies where changes of physical properties and conformation are investigated without reference to how the process actually takes place, how the forces generated are matched to the properties of the structures and environment concerned, proper time scales, or what structures or strength of structures are required.
Biorheology invites papers in which such 'molecular biorheological' aspects, whether in animal or plant systems, are examined and discussed. While we emphasize the biorheology of physiological function in organs and systems, the biorheology of disease is of equal interest. Biorheological analyses of pathological processes and their clinical implications are encouraged, including basic clinical research on hemodynamics and hemorheology.
In keeping with the rapidly developing fields of mechanobiology and regenerative medicine,
Biorheology aims to include studies of the rheological aspects of these fields by focusing on the dynamics of mechanical stress formation and the response of biological materials at the molecular and cellular level resulting from fluid-solid interactions. With increasing focus on new applications of nanotechnology to biological systems, rheological studies of the behavior of biological materials in therapeutic or diagnostic medical devices operating at the micro and nano scales are most welcome.
Abstract: The paper describes experimental techniques found useful in measuring the meniscal resistance of liquids flowing in fine capillaries and narrow channels, dyn cm−1 , the Jamin effect. The resistance has a marginal effect on the accuracy of viscosity measurements in Standard viscometers but with capillaries of lesser bore and in miniature viscometers the resistance can appreciably lower the usually acceptable accuracy while, when the dimensions approach 10 μ , the viscosity results become abnormal especially when emboli are present. The resistance appears to be associated with thin films adjacent to the menisci; the meniscal resistance of a receding…meniscus is usually much greater than the advancing one, due to the viscoelastic properties of the liquid film attached to the meniscus. This film stretches and then breaks causing rhythmic flow of an index of liquid, the flow rate being susceptible to vibrations. The meniscal resistance increases with time of standing and is highly dependent on the nature and condition of the surface. A chain of liquid indices in a capillary or a pool of liquid between parallel flats has remarkable rheological properties as Jamin, 1860, pointed out. The presence of macromols in the menisci increases the resistance, especially on standing when cementation of some kind may have occurred as with blood or serum.
Abstract: Mucoid sputum has been examined by three different rheological techniques, continuous shear, creep and oscillation. Continuous shear experiments using a Ferranti–Shirley cone and plate viscometer, are limited in their application by the viscoelastic nature of the material. In creep sputum can be represented by a simple four element mechanical model in which the moduli of rigidity and viscosities are appreciable (50–100 dyn cm−2 and 0.7–2.4 × 104 Poise respectively). Oscillation experiments over the frequency range 8 × 10−2 –10 Hz, support the view that the structure of sputum is due to the entanglement of mucoprotein chains.
Abstract: A new parallel plate instrument for the detection of a yield stress of blood is described. Its calibration and performance with materials of known properties are outlined, together with brief details of results obtained with blood. These results are shown to be consistent with those obtained by some other workers using various methods. Finally, an assessment is made of the physiological significance of a yield stress of the size suggested by the measurements.
Abstract: Further development of the cone in cone viscometer required a modification of the geometry of the measuring units as well as of the design of the instrument as a whole. These modifications permit (i) a more exact centering of the cones, (ii) a freedom from vibration and further improvement of stability of the instrument and (iii) a freedom from any possible errors due to the surface films (blood-air interface). The new geometries include the “hollow cone” and the “rhombospheroid” types. Both are suitable for study of freshly-shed or anticoagulated blood
Abstract: The primary objective of this review is a discussion of the methodology for the measurement of eye pressure. The section on aqueous humor is presented primarily as an overview to the reader so that he may have some perspective of factors which maintain the eye pressure.