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Biorheology is an international interdisciplinary journal that publishes research on the deformation and flow properties of biological systems or materials. It is the aim of the editors and publishers of
Biorheology to bring together contributions from those working in various fields of biorheological research from all over the world. A diverse editorial board with broad international representation provides guidance and expertise in wide-ranging applications of rheological methods to biological systems and materials.
The aim of biorheological research is to determine and characterize the dynamics of physiological processes at all levels of organization. Manuscripts should report original theoretical and/or experimental research promoting the scientific and technological advances in a broad field that ranges from the rheology of macromolecules and macromolecular arrays to cell, tissue and organ rheology. In all these areas, the interrelationships of rheological properties of the systems or materials investigated and their structural and functional aspects are stressed.
The scope of papers solicited by
Biorheology extends to systems at different levels of organization that have never been studied before, or, if studied previously, have either never been analyzed in terms of their rheological properties or have not been studied from the point of view of the rheological matching between their structural and functional properties. This biorheological approach applies in particular to molecular studies where changes of physical properties and conformation are investigated without reference to how the process actually takes place, how the forces generated are matched to the properties of the structures and environment concerned, proper time scales, or what structures or strength of structures are required.
Biorheology invites papers in which such 'molecular biorheological' aspects, whether in animal or plant systems, are examined and discussed. While we emphasize the biorheology of physiological function in organs and systems, the biorheology of disease is of equal interest. Biorheological analyses of pathological processes and their clinical implications are encouraged, including basic clinical research on hemodynamics and hemorheology.
In keeping with the rapidly developing fields of mechanobiology and regenerative medicine,
Biorheology aims to include studies of the rheological aspects of these fields by focusing on the dynamics of mechanical stress formation and the response of biological materials at the molecular and cellular level resulting from fluid-solid interactions. With increasing focus on new applications of nanotechnology to biological systems, rheological studies of the behavior of biological materials in therapeutic or diagnostic medical devices operating at the micro and nano scales are most welcome.
Abstract: A technique for obtaining viscometric data at very low shear rates from rotational viscometer torque decay is presented. It consists of measuring torque as a function of time and involves the assumption that the instantaneous shear rate is proportional to the rate of change of angular position. A perturbation scheme is used to show that the assumption introduces negligible error if the rate of decay is slow enough. Advantages of the technique are that (1) viscometric data at shear rates less than 1 sec−1 can be obtained easily with the simplest of equipment, and (2) readings are obtained at…once, no time delay to reach steady-state being involved. The scheme is illustrated with sample data for Newtonian and non-Newtonian fluids.
Abstract: An apparatus is described which can be used on the farm and which measures the length of thread (l ) which can be drawn from samples of bovine cervical mucus. The use of special forceps has, for the first time, made it possible to stretch the mucus without slipping at the grips. All the cows examined showed significantly higher values of l at and near the time of oestrus than at other times in the cycle (dioestrus).
Abstract: The effects of changes in association, flexibility and electrokinetic charge of red blood cells on the flow properties of their suspensions were studied using the screen filtration pressure (SFP) method and cone-plate viscometry. The SFP is dependent mainly on aggregation and adhesiveness of the cells; the volume concentration of the cells and viscosity of the plasma playing less important roles. The viscosity at moderate rates of shear depends on the volume concentration of the cells whilst aggregation and adhesiveness play a minor role. Decreasing the electrokinetic charge of the red cells by treatment with neuraminidase or uranyl nitrate, or…prehardening the cells with acetaldehyde produce no significant change in the cone-plate measurements for rates of shear >11.5 sec−1 at volume concentrations <45 per cent. At volume concentrations >50 per cent the “viscosity” of the suspensions of prehardened cells increases much more rapidly with volume concentration than for normal red cell suspensions.
Abstract: Using the Metzner and Reed method of analyzing non-Newtonian fluid flow behavior, which is based on the Rabinowitsch-Mooney equation, friction factor-Reynolds number plots were made for whole blood flowing in rigid tubes. It was found for laminar flow that blood behaved in a similar manner to other non-biologic, non-Newtonian fluids if the Reynolds number is the generalized expression proposed by Metzner and Reed. For seven different blood samples and five different tube sizes for each blood sample, it was possible to correlate all the data in a single laminar flow relationship, f = 16 / N Re…up to Reynolds number 2400 where the departure from laminar flow was abruptly evident.