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Biorheology is an international interdisciplinary journal that publishes research on the deformation and flow properties of biological systems or materials. It is the aim of the editors and publishers of
Biorheology to bring together contributions from those working in various fields of biorheological research from all over the world. A diverse editorial board with broad international representation provides guidance and expertise in wide-ranging applications of rheological methods to biological systems and materials.
The aim of biorheological research is to determine and characterize the dynamics of physiological processes at all levels of organization. Manuscripts should report original theoretical and/or experimental research promoting the scientific and technological advances in a broad field that ranges from the rheology of macromolecules and macromolecular arrays to cell, tissue and organ rheology. In all these areas, the interrelationships of rheological properties of the systems or materials investigated and their structural and functional aspects are stressed.
The scope of papers solicited by
Biorheology extends to systems at different levels of organization that have never been studied before, or, if studied previously, have either never been analyzed in terms of their rheological properties or have not been studied from the point of view of the rheological matching between their structural and functional properties. This biorheological approach applies in particular to molecular studies where changes of physical properties and conformation are investigated without reference to how the process actually takes place, how the forces generated are matched to the properties of the structures and environment concerned, proper time scales, or what structures or strength of structures are required.
Biorheology invites papers in which such 'molecular biorheological' aspects, whether in animal or plant systems, are examined and discussed. While we emphasize the biorheology of physiological function in organs and systems, the biorheology of disease is of equal interest. Biorheological analyses of pathological processes and their clinical implications are encouraged, including basic clinical research on hemodynamics and hemorheology.
In keeping with the rapidly developing fields of mechanobiology and regenerative medicine,
Biorheology aims to include studies of the rheological aspects of these fields by focusing on the dynamics of mechanical stress formation and the response of biological materials at the molecular and cellular level resulting from fluid-solid interactions. With increasing focus on new applications of nanotechnology to biological systems, rheological studies of the behavior of biological materials in therapeutic or diagnostic medical devices operating at the micro and nano scales are most welcome.
Abstract: The flow properties of whole blood and plasma were examined at low shearing stresses with a capillary viscometer. These measurements indicate that at very low shearing stress (0.5 dyn/cm2 ) whole blood has Newtonian flow characteristics but the plasma still exhibits non-Newtonian behavior. Utilizing this region of Newtonian flow along with the region that exists at high shearing stresses, it appears that the flow can be described with a one parameter equation.
vol. 1, no. 3, pp. 159-165, 1963
Abstract: When one makes erythrocyte counts in blood, one may observe irregular dark-bright stripes like a gossamer—“schlieren-effect” [Phys. , 17 , 117, 1915]—in a mixer. This peculiar phenomenon led us to make experiments to confirm whether light transparency changes or not for resting and flowing erythrocyte suspensions when light is projected on them. We have found that the transmitted light is more intensive in the flowing state than in the resting state and one of us (Kuroda ) has called this phenomenon “streaming transparency” [J. Jap. Biochem. Soc. , 26 , 403, 1954]. In order to elucidate the mechanism of…the increase in light transparency of flowing erythrocyte suspensions, a special apparatus was devised and the cause of the streaming transparency is investigated.
vol. 1, no. 3, pp. 167-182, 1963
Abstract: An equation is proposed to describe the rate of setting (i.e. rate of increase of rigidity) of both blood and milk gels under certain limited conditions. This equation is the third of a series whose first and second members represent an exponential and a power-relation respectively. The more obvious use of a logistic type of equation does not fit the experimental data. The molecular processes underlying the new equation are not yet understood and the treatment must be regarded as phenomenological, though not altogether empirical, since the equation fits the data best when independently determined time zeros are used, both…for blood and for milk.
vol. 1, no. 3, pp. 183-191, 1963
Abstract: The sigma effect concerning the flow of blood through a capillary has been discussed in connection with the distribution of the red cells from a phenomenological point of view. The distribution of the red cells is presupposed and the problem is treated by considering that the sigma effect is caused by the axial accumulation of the red cells. It is found that the assumed discontinuous distribution of the red cells across the radius of the tube gives results which most closely correspond to the measured values. A hydrodynamic interaction should exist between a wall and a particle placed near the…wall, because a further additional flow due to the wall must be considered in order to satisfy the boundary conditions at the wall. From the analysis of the experimental data we can say that the sigma effect is certainly due to the axial drift of the red cells in the blood in capillary flow, and that while the exact mechanism of the axial accumulation is not yet established, it seems likely that the hydrodynamic wall effect plays an important role in our system.
vol. 1, no. 3, pp. 193-199, 1963
Abstract: From a review of the literature of blood flow it is concluded that the physical properties of blood from different animals are very similar and that its basic rheology is reasonably well understood, except for minor uncertainties regarding the effect of anticoagulants. The major difficulty lies in applying this knowledge to hemodynamics where, in vivo, there is disagreement on the nature of the flow. In general, present-day hydrodynamics is insufficiently advanced to be applied with confidence to the problem, even as a qualitative guide.
vol. 1, no. 3, pp. 201-220, 1963