Age-dependent changes in human erythrocyte properties

Article type: Research Article

Authors: Tozzi-Ciancarelli, M.G.^a | Fedele, F.^b | Tozzi, E.^b | Di Massimo, C.^a | Oratore, A.^a | De Matteis, G.^b | D’Alfonso, A.^a | Troiani-Sevi, E.^a | Gallo, P.^b | Prencipe, M.^b

Affiliations: [a] Department of Biotechnology and Biometry, School of Medicine, Collemaggio, L’Aquila, Italy | [b] Department of Medicine, School of Medicine, Collemaggio, L’Aquila, Italy

Note: [] Accepted by: Editor T. DiPerri (Received by the Executive Editorial Office in final form 28.7.1989)

Abstract: The focus of this paper is mainly directed on the role that the structural and functional perturbations of the erythrocyte membranes could have in the incidence of abnormal microcirculation which occur with the elderly. Rheological parameters of whole blood and the activity of some enzymes involved in erythrocyte metabolism and permeability are studied.

Keywords: Microrheology, elderly, erythrocyte membrane, fluorescence

DOI: 10.3233/CH-1989-9611

Journal: Clinical Hemorheology and Microcirculation, vol. 9, no. 6, pp. 999-1007, 1989