Standardized correction of whole blood viscosity for the main determinants: A computerized system

Article type: Research Article

Authors: Bernasconi, C. | Del Santo, A. | Marrali, F. | Agostoni, A.

Affiliations: Clinica Medica V, Università degli Studi di Milano, Ospedale S.Paolo, Via di Rudinì, 8, 20142 Milano, Italy

Note: [] Accepted by: Editor H. Schmid-Schönbein

Abstract: A previously published power law fitting method for studying whole blood viscosity has been fully computerized to improve its reliability. To a large number of viscometric values for normal and pathological blood obtained by this system, multiple regression analysis was applied, relating the blood viscosity data to the main viscosity determinants, i.e., hematocrit (Hct) and plasma viscosity (ηp). The results confirm and quantify the relative importance of these two main determinants of whole blood viscosity and aggregability. Furthermore, it is possible to standardize data for these variables, to obtain indexes of “cellular component” of blood viscosity.

Keywords: blood viscosity, plasma viscosity, multiple regression analysis

DOI: 10.3233/CH-1989-9411

Journal: Clinical Hemorheology and Microcirculation, vol. 9, no. 4, pp. 633-640, 1989