Affiliations: [a] Hôpital Sainte Périne, 49, rue Mirabeau, 75016 Paris, France | [b] Laboratoire Roussel-Uclaf, Unité de recherche en nutrition 5, rue Bellini, 92806 Puteaux, France
Note: [] Accepted by: Editor M.R. Boisseau
Abstract: Elderly subjects ingested 2g or 1g of Cod Liver Oil for 6 weeks. Platelet aggregation, Blood filterability and fatty acid composition of both plasma and red cell membrane phospholipids were investigated before and after Cod Liver Oil intake. Platelet aggregation induced by low concentration of collagen, epinephrin and ADP was significantly reduced after 2g or 1g of Cod Liver Oil. Blood filterability was enhanced as well as EPA and DBA content in red cell membrane after 2g of CLO intake. There is no modification in the fatty acid composition of both plasma or red cell phospholipids after 1g of CLO. Further to their antiaggregatory effect, dietary EPA and DBA may regulate hemorheological parameters. Therefore daily intake of these n-3 fatty acids may protect against atherosclerosis and thrombosis.
