Relationships between hemodynamic indices and rheological properties of blood in primary hypertension

Article type: Research Article

Authors: Wysocki, M.^{a; b; c} | Grajek, S.^a | Bagge, U.^{b; *} | Andersson, O.K.^c | Braide, M.^b | Jasinski, K.^a | Paradowski, S.^a | Roberts, D.^d

Affiliations: [a] Institut of Cardiology, University Medical School, Poznan, Poland | [b] Laboratory of Experimental Biology, Department of Anatomy, University of Göteborg, Göteborg, Sweden | [c] Hypertension Unit, Department of Medicine I, Sahlgrenska Hospital, University of Göteborg, Göteborg, Sweden | [d] Department of Thoracic and Cardiovascular Surgery, Sahlgrenska Hospital, University of Göteborg, Göteborg, Sweden

Correspondence: [*] Correspondence: Ulf Bagge M.D., Department of Anatomy, University of Göteborg, Box 33031, S-40033, Sweden.

Note: [] Accepted by: Editor T. Di Perri

Abstract: Central hemodynamics and rheological properties of blood were studied in 15 healthy controls and 28 primary hypertensive patients (WHO 1–2) of both sexes. Hemorheological parameters: whole blood viscosity (ηB), plasma viscosity (ηp), hematocrit (HCT) and red blood cell filterability index (FI) were measured in venous blood sampled just prior to hemodynamic investigation. Plasma volume, systolic and diastolic blood pressure and cardiac output were estimated and indices: plasma volume index (PVI), blood volume index (BVI), cardiac index (CI), stroke volume index (SVI), total peripheral resistance index (TPRI) and aortic rigidity index (ARI) were calculated.

Keywords: hypertension, hemodynamics, hemorheology, blood viscosity, red blood cell deformability

DOI: 10.3233/CH-1988-8117

Journal: Clinical Hemorheology and Microcirculation, vol. 8, no. 1, pp. 113-127, 1988