Particle migration connected to rheological mechanisms in a flowing aggregated suspension. Application to white blood cells margination

Article type: Research Article

Authors: Mills, P. | Snabre, P.

Affiliations: L.B.H.P. - Universite Paris VII, 2, Place Jussieu, 75251 Paris Cedex 05, France

Note: [] Accepted by: Editor J.F. Stoltz (Received in final form by Executive Editorial Office 12.11.1986)

Abstract: Particle migration induced by rheological mechanisms in a flowing suspension is studied. Most of this paper is devoted to calculate the migration force due to aggregation of the particles which form the bulk suspension. The last section deals with the effect of particles deformability on the margination phenomena. The mechanism of white blood cell margination and the following steps leading to emigration can be fully understood owing to our theoretical model. Theory is compared to experimental data obtained by P. GAEHTGENS and his group in blood perfused glass capillaries in which white blood cells adhesion does not occur.

Keywords: Suspension, particle migration, aggregation, white blood cells

DOI: 10.3233/CH-1987-7215

Journal: Clinical Hemorheology and Microcirculation, vol. 7, no. 2, pp. 295-304, 1987