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Article type: Research Article
Authors: Cavestri, R.a | Pelucchi, A.b | Mastropasqua, B.b | Agosti, R.b | Le Grazie, C.a | Longhini, E.a
Affiliations: [a] Divisione Medica “D. e G. Campari” - Ospedale “Cittá di Sesto San Giovanni”. 20099 Sesto S. Giovanni, Milano, Italy | [b] Servizio di Broncopneumologia e Fisiopatologia Respiratoria “G. Campari” - Ospedale “Cittá di Sesto San Giovanni”, Viale Matteotti, 83 - 20099 Sesto S. Giovanni, Milano, Italy
Note: [] Accepted by: Editor G.V.F. Seaman
Abstract: Sixteen patients with recent cerebral infarction have been studied. Ten of them under,’rent hemodilution by means of erythroapheresis and have shown an increase of cerebral blood flow (CBF) and of the arterial oxygen pressure (PaO2). The oxygen delivery capacity showed no significant variations. The hemorheological parameters have been improved without a significant correlation with CBF. Furthermore the treated patients have shown a better short term clinical outcome than the untreated patients. This finding seems to indicate that the rheology of the blood is an important factor in cerebral vascular disease and that its modifications may have a useful therapeutic effect provided that all other determinants of CBF are not negatively modified.
Keywords: Cerebral Blood Flow, Cerebrovascular Disease, Hemorheology, Isovolemic Hemodilution
DOI: 10.3233/CH-1986-6504
Journal: Clinical Hemorheology and Microcirculation, vol. 6, no. 5, pp. 381-394, 1986
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