Affiliations: [a] Department of Medical Ultrasound, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China
| [b] Department of Radiology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China
Correspondence:
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Corresponding author: Yanling Zheng, The First Affiliated Hospital, Sun Yat-Sen University 7/F, 2nd Building, 58# Zhongshan Road 2, Guangzhou, 51000, China. E-mail: zhyanl@mail.sysu.edu.cn.
Note: [1] Co-first authors: Wenjuan Tong and Xiaoling Zhang.
Abstract: PURPOSE:To assess the value of conventional ultrasound (US), contrast-enhanced ultrasound (CEUS) and mammography in the diagnosis of breast lesions with calcifications. METHODS:A total of 87 breast lesions with calcification were subjected to US, CEUS and mammography and divided into 3 groups: Group A (all cases), Group A1 (31 cases who underwent US and CEUS first followed by mammography), and Group A2 (56 cases who underwent mammography first followed by US and CEUS). A receiver operating characteristic (ROC) curve analysis was performed to evaluate the diagnostic efficacy of different methods in different groups. RESULTS:In Group A, the area under the ROC curve (AUROC) of CEUS were 0.937, which were significantly higher than that of mammography (p < 0.05). In Group A1, the AUROC of CEUS were 0.842, which were not significantly different from that of US and mammography (p > 0.05). In Group A2, the AUROC of CEUS were 0.987, which were significantly higher than that of mammography and US (p < 0.05). CONCLUSION:Based on the mammography results, the combination of US and CEUS might improve the diagnostic efficacy in breast lesions with calcification.
