Laser Doppler-based measurements of periarticular blood flux can be utilized for assessment of arthritis pain: A hypothesis

Issue title: Selected Papers of the Joint Conference of the ESCHM-ISCH-ISB-2018, 2-6 July, 2018, Krakow, Poland

Guest editors: F. Jung and M. Fornal

Article type: Research Article

Authors: Motabbakani, Noura^a | Lehmann, Christian^{a; b; *}

Affiliations: [a] Department of Pharmacology, Dalhousie University Halifax, Canada | [b] Department of Anesthesia, Dalhousie University Halifax, Canada

Correspondence: [*] Corresponding author: Dr. Christian Lehmann, Dalhousie University Halifax, Department of Pharmacology, 5850 College Street, B3H 4R2, Halifax, Nova Scotia, Canada. E-mail: chlehmann@dal.ca.

Abstract: Arthritis often presents with serious pain of the affected joints. The pain results mainly from underlying inflammatory processes initiated by the immune response to the degenerative structural changes within the joints and is associated with microvascular vasodilation that increases articular blood flow. Laser Doppler-based methods facilitate reliable quantification of microvascular perfusion. We hypothesize that laser Doppler-based measurements of periarticular blood flux can be utilized for assessment of arthritis pain in patients.

DOI: 10.3233/CH-189408

Journal: Clinical Hemorheology and Microcirculation, vol. 71, no. 2, pp. 171-174, 2019