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Article type: Research Article
Authors: Irace, Concetta | Carallo, Claudio | Scavelli, Faustina | Loprete, Antonio | Merante, Valentina | Gnasso, Agostino
Affiliations: Dipartimento di Medicina Sperimentale e Clinica “G. Salvatore”, “Magna Græcia” University, Catanzaro, Italy
Note: [] These authors have contributed equally to the manuscript.
Note: [] These authors have contributed equally to the manuscript.
Note: [] Corresponding author: Agostino Gnasso, MD, “Magna Græcia” University, University Campus, “S. Venuta”, Germaneto, 88100 Catanzaro, Italy. Tel.: +39 09613697039; Fax: +39 09613647250; E-mail: gnasso@unicz.it
Abstract: Objective: A direct relationship between blood pressure and viscosity has frequently been reported, although clear data are not available. To better understand the relationship between these two variables, we evaluated blood viscosity and blood pressure in a group of healthy subjects without cardiovascular risk factors. Methods: Healthy subjects were selected from participants in a campaign of prevention of cardiovascular disease (n = 103). They underwent blood sampling for measurement of plasma and blood viscosity, haematocrit, blood lipids and glucose. The quantity and distribution of body fat was assessed by body mass index and waist/hip ratio, respectively. Results: Systolic blood pressure (SBP) correlated significantly with age (r = 0.222) and waist/hip ratio (r = 0.374). Diastolic blood pressure (DBP) correlated significantly with waist/hip ratio (r = 0.216), haematocrit (r = 0.333) and blood viscosity (r = 0.258). Multiple linear regression analyses demonstrated that the only variable significantly associated with SBP was age, while haematocrit was the only variable significantly associated with DBP. Blood viscosity was closely related to waist/hip ratio. Conclusion: These findings show that SBP, in healthy subjects, is not influenced by haematocrit and blood viscosity. In contrast, DBP is related to the values of haematocrit. Among classical cardiovascular risk factors, waist/hip ratio is closely related to blood viscosity.
Keywords: Blood viscosity, blood pressure, CHD risk factors
DOI: 10.3233/CH-2011-1506
Journal: Clinical Hemorheology and Microcirculation, vol. 51, no. 1, pp. 35-41, 2012
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