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Article type: Research Article
Authors: Kumaravel, M. | Singh, Megha
Affiliations: Biomedical Engineering Division, Indian Institute of Technology, Madras 600 036, India
Abstract: Aggregation process of erythrocytes in mammals is determined. This process is described in terms of parameters which are determined by sequential recording and analysis of the He-Ne laser light transmission data after passing through erythrocyte suspension at hematocrit 5%. These parameters provide information on variation in aggregate size, sedimentation time, total number of fluctuations due to formed aggregates and process completion time. The analysis shows that in horse blood samples the formation of a large number of aggregates is significantly faster compared to that in human and buffalo samples. Their mobility as determined by sedimentation time also shows a similar pattern. The erythrocyte suspensions of cow, goat and rabbit do not show any fluctuation which indicates that these cells remain in monodisperse state over a long duration. The time taken for clearance of observation volume is the maximum for goat (10.6 hr) and minimum for horse (8.1 min).
Keywords: Sequential analysis, erythrocyte aggregation, mammals, transmitted intensity
DOI: 10.3233/CH-1995-15302
Journal: Clinical Hemorheology and Microcirculation, vol. 15, no. 3, pp. 291-304, 1995
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