Red cell deformability and erythrocyte lipids in hypertension

Article type: Research Article

Authors: Annapurna, V. | Puniyani, R.R. | Gupte, R.V.

Affiliations: School of Biomedical Engineering, I.I.T., Bombay,India

Note: [] Accepted by: Editor L. Dintenfass

Abstract: Red cell membrane structural components; the cholesterol and phospholipids are quantified in cases of Hypertension, in order to assess their possible role in contributing to the red cell rigidity in Hypertension. The results indicate a strong positive correlation between the ratio of cholesterol: phospholipid and red cell deformability. Considering the individual correlations, phospholipids show significant negative correlation indicating its importance in regulating the red cell membrane permeability in chronic hypertensives.

Keywords: Hypertension, Deformability, Cholesterol, Phospholipids

DOI: 10.3233/CH-1990-10110

Journal: Clinical Hemorheology and Microcirculation, vol. 10, no. 1, pp. 95-101, 1990