Affiliations: National Cardiovascular Center Research Institute, Suita, Osaka, Japan
Note: [] Accepted by: Editor E. Fukada
Abstract: The supply of oxygen to tissue from capillaries may be influenced by hemorheological factors. A hemorheological model is developed for elucidating which factors play a major role in the oxygen transport to tissue. For a capillary tissue unit, a modified cylindrical model of Krogh is used. For blood, two fluids model of red blood cells (RBCs) and plasma is used where hemoglobin release effect is included. Non-equilibrium flows as well as equilibrium flows are examined for various parameters (total flow Q or RBC velocity Vr, discharge hematocrit Hd and capillary hematocrit Hc). In equilibrium flow, Hd and Q determine the oxygen transport. In non-equilibrium flow, Hc also becomes important. Especially, hemoglobin release effect becomes significant in low Hc flow, which affects the area of lethal region in tissue.
Keywords: capillary flow, hematocrit, hemorheology, non-equilibrium flow, oxygen transfer
DOI: 10.3233/BIR-1983-20517
Journal: Biorheology, vol. 20, no. 5, pp. 603-614, 1983
