Numerical investigation of the effects of blood rheology and wall elasticity in abdominal aortic aneurysm under pulsatile flow conditions

Article type: Research Article

Authors: Bilgi, Coşkun^a | Atalık, Kunt^a;

Affiliations: [a] Mechanical Engineering Department, Boğaziçi University, Bebek, Istanbul, Turkey

Correspondence: [*] Corresponding author: Kunt Atalık, Mechanical Engineering Department, Boğaziçi University, 34342 Bebek, Istanbul, Turkey. E-mail: atalik@boun.edu.tr

Abstract: BACKGROUND:Previous studies on aneurysm modeling have focused on the blood rheology and vessel elasticity separately. The combined effects of blood shear thinning properties and wall elasticity need to be revealed. OBJECTIVE:To provide insights on how pulsatile hemodynamics vary with blood rheology and vessel elasticity for a developed abdominal aortic aneurysm (AAA). METHOD:An Arbitrary Lagrangian-Eulerian fluid-solid interaction method is adopted with the Newtonian and the shear thinning Carreau constitutive models for the fluid with the linearly elastic and the hyperelastic Yeoh models for the vessel. Finite element based numerical solver is used to simulate the blood flow in the AAA. RESULTS:Newtonian model overestimates the velocity values compared to the Carreau model and the difference in the velocity field increases as the shear rate decreases at the instances of the cardiac cycle. The rigid walled simulations display higher deviations in the velocity and wall shear stress with the fluid rheology. The risk indicators show that Newtonian assumption combined with the linearly elastic model may overlook degeneration risk of arterial tissue. CONCLUSIONS:Newtonian assumption for the blood as well as modelling the arterial wall as linearly elastic lead to significant differences in oscillatory hemodynamic properties with respect to the use of Carreau fluid together with hyperelastic vessel model, even in large vessel aneurysms.

Keywords: Pulsatile hemodynamics, fluid-solid interaction (FSI), abdominal aortic aneurysm (AAA), blood rheology, blood vessel modeling, oscillatory shear index (OSI)

DOI: 10.3233/BIR-180202

Journal: Biorheology, vol. 56, no. 1, pp. 51-71, 2019