Journal of Pediatric Infectious Diseases - Volume 6, issue 3

Authors: Basu, Sriparna | Verma, Nishant | Kumar, Ashok

Article Type: Research Article

Abstract: Cytomegalovirus (CMV) is one of the most common congenital viral infections in humans. It can follow both primary and recurrent maternal infections and is an important cause of morbidity and mortality in newborns. The effects of congenital CMV infection vary widely from asymptomatic illness to a congenital syndrome with microcephaly, jaundice, hepatosplenomegaly and petechiae. Infants who are asymptomatic at birth may still present with sensorineural hearing loss, mental retardation and neuromuscular defects at a …later age. We report a full term, small-for-gestational age neonate with congenital CMV infection who presented with unusual clinical features, including choanal atresia, digital hypoplasia, simian crease, blueberry muffin rash, cortical atrophy and hemiparesis. Show more

Keywords: Blueberry muffin rash, congenital cytomegalovirus infection, choanal atresia, digital hypoplasia, hemiparesis, simian crease

DOI: 10.3233/JPI-2011-0317

Citation: Journal of Pediatric Infectious Diseases, vol. 6, no. 3, pp. 221-225, 2011

Authors: Abelian, Arthur | Pritchard, Ian

Article Type: Research Article

Abstract: The sensitivity of conventional microbiological techniques for the diagnosis of neonatal bacterial meningitis is often inadequate. We review our data, discuss recent technological advances and argue that polymerase chain reaction targeted against microorganisms commonly involved in this condition could offer important advantages in the diagnosis and management of this condition.

Keywords: Neonatal bacterial meningitis, polymerase chain reaction

DOI: 10.3233/JPI-2011-0316

Citation: Journal of Pediatric Infectious Diseases, vol. 6, no. 3, pp. 227-229, 2011