Biomedical Spectroscopy and Imaging - Volume 8, issue 3-4

Authors: Barbosa, Luidy Darllan | Sussulini, Alessandra

Article Type: Research Article

Abstract: The applications of laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) in biomedical research are progressively increasing in the last decade. The main advantage of this powerful analytical technique is the ability to perform multi-elemental analysis directly from biological samples, such as tissues, organs, and single cells, with minimal sample preparation. This feature is particularly important for studies regarding disease biomarkers and mechanism of action of drugs. In this mini-review, the recent advances in the use of LA-ICP-MS for the analysis of biological samples will be discussed, as well as representative biomedical applications.

Keywords: Laser ablation, mass spectrometry, tissue analysis, single cell analysis, biomedicine

DOI: 10.3233/BSI-200193

Citation: Biomedical Spectroscopy and Imaging, vol. 8, no. 3-4, pp. 47-54, 2019

Authors: Rohman, Abdul | Windarsih, Anjar | Lukitaningsih, Endang | Rafi, Mohamad | Betania, K. | Fadzillah, Nurrulhidayah A.

Article Type: Review Article

Abstract: Fourier transform infrared (FTIR) and Raman spectroscopy are complementary techniques, typically called vibrational spectroscopy. Both techniques allow simple, rapid, non-destructive, specific, providing fingerprint spectra, and real-time analytical method for analysis of molecules in different states. Besides, these methods are simple without any excessive sample pre-treatment, therefore, they are sometimes called as “green analytical methods”. Biofluids have several biomolecules such as lipid, protein, nucleic acids, and carbohydrates. These biomolecules can be used as biomarkers to detect some types of diseases, since biomolecules are in direct contact with the human organs. FTIR and Raman spectra of biofluids are complex in nature, therefore …sophisticated statistical techniques, known as chemometrics, must be used to solve the analytical problems related to quantitative analysis purposes. The objective of this review is to show the capability of FTIR and Raman spectroscopic techniques in combination with chemometrics techniques to analyze the biomolecules in biofluids through an extensive literature review. During performing this review, several databases in Science citation index, Scopus PubMed, and Google Scholar related to the topics are identified and downloaded. With the present review, it is known that FTIR and Raman techniques are rapid method for screening certain diseases by identifying the level changes of some biomolecules. In the future, this method will be widely used for clinicians as new diagnostic tools for many diseases. Show more

Keywords: FTIR spectroscopy, Raman spectroscopy, chemometrics, biomolecules, biofluids

DOI: 10.3233/BSI-200189

Citation: Biomedical Spectroscopy and Imaging, vol. 8, no. 3-4, pp. 55-71, 2019

Authors: Latif, Rachid | Saddik, Amine

Article Type: Research Article

Abstract: The high flexibility of the heterogeneous system based on CPU-GPU and CPU-FPGAoffer us huge performance in terms of processing time and resource optimization. We can use these systems in all areas provided that we have studied the adequacy between the algorithm and the architecture, this adequacy technique is called hardware software co-design. Today, the need for embedded systems is an irreplaceable reality, especially when we talk about real-time systems. Among the most well-known embedded systems are FPGAs, this system is based on the parallelization of algorithms via the pipline principle. In this work, we present the application of the heterogeneous …system in the biomedical field, in particular the cardiac signals provided by the electrocardiogram and the different ECG signal filtering techniques. And also, we will proposing an embedded implementation of the ADTF filter in a homogeneous architecture (FPGA). And also, the heterogeneous architecture via the HLS OpenCL. Show more

Keywords: Heterogeneous system, CPU-GPU, CPU-FPGA, ECG signal

DOI: 10.3233/BSI-200192

Citation: Biomedical Spectroscopy and Imaging, vol. 8, no. 3-4, pp. 73-80, 2019

Authors: Mosaif, Afaf | Rakrak, Said

Article Type: Research Article

Abstract: Background: In hospitals, patients placed in Intensive Care Units need constant and close monitoring and require special equipment to ensure their normal bodily functions. The problem is how to continuously monitor each patient while ensuring the privacy of their information? And what technology to choose as a medium of wireless communication? Objective: The aim of this work is to propose a novel wireless system for surveillance in intensive care units in hospitals. This system will have no interference issue with hospital equipment and will ensure the privacy of patient information. In addition, it has many other functionalities that …facilitate patient surveillance. Methods: Interested by the challenge of the reliable transmission of visual data in the proposed system, a simulation under ns-3 is developed to evaluate the performance of the used wireless technology and to compare it with Wi-Fi channels in terms of video transmission in a Wireless Visual Sensor Network. Results: Our results reveal the high fidelity of the reconstructed videos transmitted via the used technology in our system compared to those transmitted via Wi-Fi channels. Conclusion: The proposed system will provide a high level of security, high speed of data transmission, low energy consumption and it will have no interference issue with the hospital equipment. Show more

Keywords: Biomedical engineering, light-fidelity, telemedicine, video transmission, visible light communication, wireless sensors

DOI: 10.3233/BSI-200191

Citation: Biomedical Spectroscopy and Imaging, vol. 8, no. 3-4, pp. 81-92, 2019