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Acoustic characteristics of vowel sounds in patients with Parkinson disease

Issue title: Balance and Vestibular Function

Guest editors: Brian D. Greenwald and James M. Gurley

Article type: Research Article

Authors: Bang, Young-Ima; b | Min, Kyunghoonc | Sohn, Young H.d | Cho, Sung-Raea; e; f; g; h; *

Affiliations: [a] Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul, Korea | [b] Speech-Language Clinic, Rehabilitation Hospital, Yonsei University Medical Center, Seoul, Korea | [c] Department of Rehabilitation Medicine, CHA Bundang Medical Center, CHA University, Korea | [d] Department of Neurology and Brain Research Institute, Yonsei University College of Medicine, Seoul, Korea | [e] Brain Korea 21 for Medical Science, Yonsei University, Seoul, Korea | [f] Nano Science and Technology, Yonsei University, Seoul, Korea | [g] Yonsei Biomedical Research Institute, Avison Biomedical Research Center, Seoul, Korea | [h] Rehabilitation Institute of Neuromuscular Disease, Yonsei University College of Medicine, Seoul, Korea

Correspondence: [*] Address for correspondence: Sung-Rae Cho M.D., Ph.D., Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, 134 Shinchon-dong, Seodaemun-gu, Seoul, 120-752, Korea. E-mail: srcho918@yuhs.ac

Keywords: Parkinson disease, acoustic analysis, vowel space area, centralization

DOI: 10.3233/NRE-130887

Journal: NeuroRehabilitation, vol. 32, no. 3, pp. 649-654, 2013

Published: 21 May 2013
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Abstract

The purpose of this study was to define the acoustic voice and speech characteristics of patients with Parkinson disease (PD). Seven female patients with PD and seven female healthy controls participated in this study. Each subject was instructed to vocalize extended corner vowels (/a/, /e/, /i/, /u/) three times for at least 5 seconds at a comfortable voice loudness and tone. The voice was analyzed using the Praat program. As a result, female patients with PD showed a significant increase in jitter and noise-to-harmonics ratio (NHR). In addition, F1 and F2 among the PD patients demonstrated asymmetric centralization of unrounded vowels (/a/, /e/, /i/) in high/low/front/back positions of the tongue, consequently leading to a significant decrease in vowel space area, compared to healthy controls. This study showed the acoustic characteristics of vowel sounds not only by laryngeal variables such as abnormal jitter and NHR, but also by articulatory variables such as asymmetric centralization and reduced vowel space area in female patients with PD. Therefore, it is important to use these objective and sensitive variables to evaluate the status or severity of hypokinetic dysarthria in patients with PD.

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