Affiliations: [a] Department of Occupational Therapy, Steinhardt School of Culture, Education, and Human Development, New York University, New York, NY, USA | [b] Rusk Institute of Rehabilitation Medicine, New York University Langone Medical Center, New York, NY, USA | [c] Kessler Foundation Research Center, Neuropsychology and Neuroscience Laboratory, West Orange, NJ, USA | [d] Department of Physical Medicine and Rehabilitation, UMDNJ-New Jersey Medical School, Newark, NJ, USA | [e] Schizophrenia Research Center, Nathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, USA | [f] Department of Psychiatry, NYU School of Medicine, New York, NY, USA | [g] Department of Psychology, City University of the City College of New York, New York, NY, USA
Correspondence:
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Corresponding author: Gerald T. Voelbel, Ph.D., Steinhardt School of Education, Culture, and Human Development, New York University, 35 West 4th Street, 11th Floor, New York, NY 10012, USA. E-mail: gv23@nyu.edu
Abstract: Diffusion tensor imaging (DTI) has widely been used to investigate the microstructural damage of white matter tracts that occur in individuals with traumatic brain injury (TBI). In the current review, we discuss the white matter regions which are commonly affected in adults with TBI. We also describe the current literature that has utilized DTI to investigate the relationship between microstructural integrity with neuropsychological performance and clinical outcome measures. Finally, a model is presented of the potential utilization of DTI as a biomarker of efficacy in neurorehabilitation for individuals with TBI.
