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Article type: Research Article
Authors: Gall, Carolina; * | Fedorov, Anton B.b | Ernst, Lisaa | Borrmann, Antoniaa | Sabel, Bernhard A.a
Affiliations: [a] Otto-von-Guericke University of Magdeburg, Medical Faculty, Institute of Medical Psychology, Magdeburg, Germany | [b] EBS Technologies GmbH, Kleinmachnow, Germany
Correspondence: [*] Address for correspondence: Carolin Gall, Institute of Medical Psychology, Leipziger Str. 44, 39120 Magdeburg, Germany. Tel.: +49 391 672 1807; Fax: +49 391 672 1803; E-mail: Carolin.Gall@med.ovgu.de
Abstract: Background:Visual field defects after optic nerve damage typically show a limited capacity for spontaneous and treatment-induced recovery. Objective:Repetitive transorbital alternating current stimulation (rtACS) was applied to the damaged optic nerve to evaluate visual functions after stimulation. Methods:A 27-years-old male patient suffering left optic nerve atrophy with nearly complete loss of vision 11 years after atypical traumatic damage was treated transorbitally with biphasic 10–15 pulse trains of rtACS (10–30 Hz, < 600 μA, 30–40 min daily for 10 days) which produced phosphenes. Results:After rtACS treatment detection ability of super-threshold stimuli increased from 3.44% to 17.75% and mean perimetric threshold from 0 dB to 2.21 dB at final diagnostics. Conclusion:This improvement of vision may be due to increased neuronal synchronization, possibly involving strengthening of synaptic transmission along the central visual pathway.
Keywords: Alternating current, electric stimulation, traumatic optic neuropathy, vision recovery
DOI: 10.3233/NRE-2010-0617
Journal: NeuroRehabilitation, vol. 27, no. 4, pp. 335-341, 2010
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