Affiliations: Departments of Radiology and Pediatrics, Cincinnati Children’s Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, OH, USA | Divisions of Neonatology and Pulmonary Biology, Cincinnati Children’s Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, OH, USA
Note: [] Corresponding author: Beth M. Kline-Fath, Cincinnati Children’s Hospital Medical Center, Department of Radiology, MLC 5031, 3333 Burnet Avenue, Cincinnati, OH 45229, USA. Tel.: +1 513 636 1856; Fax: +1 513 636 1388; E-mail: Beth.Kline-Fath@cchmc.org.
Abstract: Understanding the pathophysiology, imaging and correlative preterm outcome of white matter ischemic injury is important to improve neonatal clinical practices and to support preventative therapies. This article will focus on these topics in an attempt to provide greater understanding of premature white matter disease in this fragile age group.
Keywords: Prematurity, oligodendrocytes, magnetic resonance imaging, diffusion tensor imaging, magnetic resonance spectroscopy
