Affiliations: Virology and immunology Unit Cancer biology Department
and Clinical Pathology Department National Cancer Institute, Cairo, Egypt | Virology and Immunology Laboratory, King Fahd General
Hospital, Jeddah, Saudia Arabia | Oncology Diagnostic Unit, Suez Canal University,
Egypt
Note: [] Address for correspondence: Gamal M. Mabrouk MD, PhD, Oncology
Diagnostic Unit, Ain Shams Faculty of Medicine, Abbassia, Cairo, Egypt. Tel.:
+202 6859928; E-mail: gamal_mabrouk@ hotmail.com
Abstract: We screened blood donors in one center in Saudi Arabia for a safety
transfusion. We found that among 5043 blood donors negative for HCV and HIV,
the incidence of HBsAg positivity was 2.97%. antibody was measured (HBcIg) in
HBsAg negative donors, we observed that 21.47% B virus. The HBcIg positive
blood was further screened for HBsAb and the specimens were found to be
reactive in 81.54%. data blood transfusion was permissible from donors who
showed HBsAg negativity, HBcIg positive and HBsAb reactive blood. In order to
ensure safety transfusion an aliquot of specimens (n=80) was further analyzed
for HBV DNA by PCR. We found only one specimen positive with incidence of
1.25%. the previously mentioned donors to emergencies.
Keywords: blood units, HBsAg, HBcIg, HBV DNA, Saudi
