Affiliations: International Center for Artificial Organs and Transplantation, Painesville, OH, USA
Note: [] Address for correspondence: Paul S. Malchesky, DEng, 10 W. Erie St. #200, Painesville, OH 44077, USA. Tel.: +1 440 358 1102; Fax: +1 440 358 1104; E-mail: Paulsmalchesky@aol.com
Abstract: Dr. Yukihiko Nosé made many contributions to medical science and in particular in the area of artificial organ technologies and their clinical applications. His passing was a great loss not only to many individuals but also to the field. His enthusiasm and passion for his work was very positive on those with whom he worked while inspiring others in friendly competition. It is very difficult to recount his many accomplishments. I have outlined those developments that I was directly involved with him at the Cleveland Clinic. These developments may be grouped under the heading of Metabolic and Immunologic Support, the name given to our research team. I hope in some small way this review also gives credit to the contributions of the many scientific and clinical professionals that were part of our teams through the years as noted in the extensive reference list provided and the support of the many industrial and corporate sponsors that we were privileged to be associated with and their developments that we studied, improved on, and applied.
