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Article type: Research Article
Authors: Ali, Saqiba | Farooq, Imrana; | Al-Thobity, Ahmad M.b | Al-Khalifa, Khalifa S.c | Alhooshani, Khalidd | Sauro, Salvatoree; f
Affiliations: [a] Department of Biomedical Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia | [b] Department of Substitutive Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia | [c] Department of Preventive Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia | [d] Department of Chemistry, King Fahd University of Petroleum and Minerals, Dhahran, Saudi Arabia | [e] Departamento de Odontología, Facultad de Ciencias de la Salud, Universidad CEU-Cardenal Herrera, C/Del Pozos/n, Alfara del Patriarca, Valencia, Spain | [f] Department of Therapeutic Dentistry, Sechenov University Russia, Moscow, Russia
Correspondence: [*] Corresponding author: Imran Farooq, Department of Biomedical Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam (31441), Saudi Arabia. Tel.: +966 133331426; Mobile: +966 507643702; E-mail: drimranfarooq@gmail.com
Abstract: BACKGROUND:Many novel biomaterials have been incorporated in toothpastes to promote remineralization of tooth structure. OBJECTIVES:This study was carried out to compare the discrepancies between declared and actual total fluoride (TF) or total soluble fluoride (TSF) concentration of two modern toothpastes containing bioactive glasses; these were also assessed for their remineralization potential. MATERIALS AND METHODS:The TF and TSF concentration were assessed using a fluoride ion selective electrode. Enamel remineralization was evaluated through micro-hardness analysis. Eighteen enamel blocks were divided into three groups: 1 (n = 6; control), 2 (n = 6; Novamin® toothpaste), and 3 (n = 6; BiominF® toothpaste). The specimens were demineralized by 6 wt% citric acid (pH = 2.2). Subsequently, the specimens in group 1 were kept in artificial saliva (AS), while the specimens in groups 2 and 3 were stored in AS + Novamin® and AS + Biomin®, respectively. RESULTS:Both Novamin® or BiominF® showed less TF concentration than their label claims. BiominF® had more TF and TSF compared to Novamin® (p < 0.05). The BiominF® toothpaste presented higher micro-hardness values on remineralization.CONCLUSION: BiominF® toothpaste demonstrated more fluoride content and greater potential to promote remineralization of demineralized human enamel compared to Novamin®.
Keywords: Bioactive glass, demineralization, enamel, fluoride, remineralization
DOI: 10.3233/BME-191069
Journal: Bio-Medical Materials and Engineering, vol. 30, no. 5-6, pp. 487-496, 2019
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