Affiliations: Department of Neurosurgery, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830054, China
Correspondence:
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Corresponding author: Xiao-Jiang Cheng, Department of Neurosurgery, The First Affiliated Hospital of Xinjiang Medical University, No. 137 of Liyushannan Road, Urumqi, Xinjiang Uyghur Autonomous Region 830054, China. Tel.: +86 13179837560; E-mail: chengxiaojiang0923@163.com.
Note: [*] These authors equally contributed to the work.
Abstract: Objective:To observe the short-term efficacy of Pipeline embolization divice (PED) for the treatment of complex intracranial aneurysms. Methods:The clinical data of 29 consecutive patients with 32 intracranial aneurysms treated with PED between April 2015 to September 2016 were analyzed retrospectively. There were 3 small aneurysm, 15 large aneurysms, 8 giant aneurysms, 5 fusiform ayneurysms and 1 recidivation. The vessels include 25 anterior circulation and 4 posterior circulation. Results:We treated 31 aneurysms with 30 PEDs and all of the stents were implanted successfully. 1 case of single aneurysm was multiple divices implanted and 1 case of 3 aneurysms were treated by single PED. 12 of the 29 patients were implanted PED only, 17 were implanted PED with coils, 2 underwent balloon remodeling after the PED implanted. The ostia of 19 ophthalmic arteries, 10 posterior communicating arteries, 4 posterior inferior cerebellar arteries and 1 anterior cerebral artery were covered by PED during procedures; 1 ophthalmic arteries and 1 posterior communicating artery disappeared, no branch vessels occlusion and parent artery stenosis occurred.Hemorrhagic complacations occurred in 2 patients, 2 hours and 5 days after procedure respectively. Radiographic follow-up examnations were carried out in 24 patients and revealed complete occlusion in 21 patients, uncomplete occlusion in 3 patients. No neurological injure occurred in 27 patients who received a clinical follow-up. Conclusion:PED provide a safe and effective methord for the treatment of intracranial complex aneurysms like wide-neck aneurysms, fusiform aneurysms, giant aneurysms in low risk of procedural complications and high rates of aneurysm occlusion.
