Study on the corrosion resistance and anti-infection of modified magnesium alloy

Article type: Research Article

Authors: Bai, Ningning | Tan, Cui | Li, Qing^{; *} | Xi, Zhongxian

Affiliations: School of Chemistry and Chemical Engineering, Southwest University, No. 2 Tiansheng Road, BeiBei District, Chongqing, 400715, P.R. China

Correspondence: [*] Corresponding author. Tel.: +86 023 68252360; Fax: +86 02368387675; E-mail: liqingswu@163.com.

Abstract: In this paper, a low-cost and multifunctional hydroxyapatite (HA)/pefloxacin (PFLX) drug eluting layer is coated on magnesium (Mg) alloy through a simple hydrothermal and dip process. The drug PFLX could provide effective prevention for bone infection and inflammation due to its broad-spectrum antibacterial property. And HA would promote the growth of new bone and further improve the biocompatibility of implants. Besides, both PFLX and HA exhibits excellent corrosion protection for Mg alloy substrate. This coating is of great value for improving the application of Mg alloy as biomaterials.

Keywords: Magnesium alloy, biomaterials, anti-corrosion, anti-infection, biocompatibility

DOI: 10.3233/BME-171681

Journal: Bio-Medical Materials and Engineering, vol. 28, no. 4, pp. 339-345, 2017