Analysis of intima-media thickness of carotid artery and lipoprotein-associated phospholipase A2 in coronary heart diseases of different types

Subtitle:

Article type: Research Article

Authors: Li, Ya

Affiliations: Affiliated Hospital of Hebei University, BaoDing 071000, Hebei, China. Tel.: +86 15833123569; E-mail: diablb@126.com

Abstract: OBJECTIVE: To analyze intima-media thickness (IMT) of carotid artery and lipoprotein-associated phospholipase A2 (Lp-PLA2) in patients with coronary heart diseases of different types. METHODS: A total of 1000 patients with suspicious coronary heart diseases were selected for carotid ultrasonography, coronary CT and Lp-PLA2, and divided into normal group, coronary atherosclerosis group and coronary heart disease group. RESULTS: Statistical significance was observed in differences of IMT and Lp-PLA2 between normal group, coronary atherosclerosis group and coronary heart disease group. IMT and Lp-PLA2 were positively correlated. The worse the coronary heart disease, the higher the IMT or Lp-PLA2 values. CONCLUSION: IMT and Lp-PLA2 ware closely correlated with coronary artery stenosis. IMT and Lp-PLA2 have certain predicting values for severity of coronary heart diseases. The combination of the two can improve noninvasive diagnosis of coronary heart diseases.

Keywords: IMT, Lp-PLA2, coronary heart disease

DOI: 10.3233/thc-150947

Journal: Technology and Health Care, vol. 23, no. s1, pp. S147-S150, 2015