Searching for just a few words should be enough to get started. If you need to make more complex queries, use the tips below to guide you.
Article type: Research Article
Authors: Battula, N.a | Menezes, V.a; * | Bhalekar, S.b | Bhalekar, S.H.b | Nejad, S.M.c | Hosseini, H.c
Affiliations: [a] Department of Aerospace Engineering, Indian Institute of Technology Bombay, Powai, Mumbai, India | [b] Departments of ENT & Pathology, D.Y. Patil University School of Medicine, Nerul, Navi Mumbai, India | [c] Department of Bioelectrics, Institute of Pulsed Power Science, Kumamoto University, Kumamoto, Japan
Correspondence: [*] Corresponding author: V. Menezes, Department of Aerospace Engineering, Indian Institute of Technology Bombay, Powai, Mumbai 400076, India. Tel.: +91 9920238130; Fax: +91 22 2572 2602; E-mail: viren@aero.iitb.ac.in.
Abstract: A needle-free vaccine/drug injector that works by virtue of the impulse of a moving shock wave is presented in this communication. The device can deliver controlled micro-volumes of liquid vaccines into skin and soft tissue targets in human with minimal invasion. The operation of the injector was investigated by delivering a dyed liquid into human skin samples and soft tissue models. The depth of penetration of the liquid was examined by histology of the targeted human skin samples. The delivery mechanics and the depth of penetration were analyzed theoretically with an elastic model for the skin and a viscoelastic model for the soft tissue targets, and a good agreement with experiments was observed. The current liquid vaccine/drug delivery technique can reduce pain, trauma and contamination, and can offer a cost-effective, needle-free, health-care solution.
Keywords: Impulse, shock wave, needle-free, vaccine/drug delivery
DOI: 10.3233/THC-171022
Journal: Technology and Health Care, vol. 25, no. 6, pp. 1131-1138, 2017
IOS Press, Inc.
6751 Tepper Drive
Clifton, VA 20124
USA
Tel: +1 703 830 6300
Fax: +1 703 830 2300
sales@iospress.com
For editorial issues, like the status of your submitted paper or proposals, write to editorial@iospress.nl
IOS Press
Nieuwe Hemweg 6B
1013 BG Amsterdam
The Netherlands
Tel: +31 20 688 3355
Fax: +31 20 687 0091
info@iospress.nl
For editorial issues, permissions, book requests, submissions and proceedings, contact the Amsterdam office info@iospress.nl
Inspirees International (China Office)
Ciyunsi Beili 207(CapitaLand), Bld 1, 7-901
100025, Beijing
China
Free service line: 400 661 8717
Fax: +86 10 8446 7947
china@iospress.cn
For editorial issues, like the status of your submitted paper or proposals, write to editorial@iospress.nl
如果您在出版方面需要帮助或有任何建, 件至: editorial@iospress.nl