Simulation of stress urinary incontinence for in-vitro studies

Article type: Research Article

Authors: Marti, Florian^{a; b} | Blunschi, Nadine^a | Leippold, Thomas^c | Müller, Bert^{a; b; *}

Affiliations: [a] Computer Vision Laboratory, ETH Zürich, Switzerland | [b] Biomaterials Science Center, University of Basel, Switzerland | [c] Department of Urology, Kantonsspital St. Gallen, Switzerland

Correspondence: [*] Address for correspondence: Prof. Dr. Bert Müller, Biomaterials Science Center, c/o University Hospital Basel, CH-4031 Basel, Switzerland. Tel.: +41 61 265 9660; Fax: +41 61 265 96 99; E-mail: bert.mueller@unibas.ch.

Abstract: A simulation system that generates dynamic bladder pressures for the use of testing and examining artificial urinary sphincters is designed, implemented, and compared to in-vivo measurements of Valsalva and coughing profiles. Cylinder and piston, which are integrated into the universal testing machine, simulating the bladder are connected with explanted sow urethras. The AMS 800™ artificial urinary sphincter closes the urethra with well-defined external pressures. In order to select appropriate profiles for the bladder pressure, 34 Valsalva and coughing profiles of 6 patients were evaluated with respect to amplitude, pressure raise, dwell time, and half width.

Keywords: Artificial urinary sphincter, bladder simulation, cough profiles, cough profiles simulation, valsalva pressure, valsalva profiles simulation

DOI: 10.3233/THC-2008-16201

Journal: Technology and Health Care, vol. 16, no. 2, pp. 77-83, 2008