Liver acquisition with acceleration volume acquisition gadolinium-enhanced magnetic resonance combined with T2 sequences in the diagnosis of local recurrence of rectal cancer

Article type: Research Article

Authors: Cao, Wuteng^{a; 1} | Li, Fangqian^{a; 1} | Gong, Jiaying^a | Liu, Dechao^a | Deng, Yanhong^b | Kang, Liang^c | Zhou, Zhiyang^{a; *}

Affiliations: [a] Department of Radiology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China | [b] Department of Oncology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China | [c] Department of Colorectal Surgery, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China

Correspondence: [*] Corresponding author: Zhiyang Zhou, Department of Radiology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou 510655, China. Tel.: +86 13926492838; Fax: +86 020 38254054; E-mail: zhouzyang@hotmail.com.

Note: [1] They contributed equally to this work.

Abstract: To investigate the efficacy of liver acquisition with acceleration volume acquisition (LAVA) gadolinium-enhanced magnetic resonance (MR) sequences and to assess its added accuracy in diagnosing local recurrence (LR) of rectal cancer with conventional T2-weighted fast spin echo (FSE) sequences. Pelvic MRI, including T2-weighted FSE sequences, gadolinium-enhanced sequences of LAVA and T1-weighted FSE with fat suppression, was performed on 225 patients with postoperative rectal cancer. Two readers evaluated the presence of LR according to “T2” (T2 sequences only), “T2 + LAVA-Gad” (LAVA and T2 imaging), and “T2 + T1-fs-Gad” (T1 fat suppression-enhanced sequence with T2 images). To evaluate diagnostic efficiency, imaging quality with LAVA and T1-fs-Gad by subjective scores and the signal intensity (SI) ratio. In the result, the SI ratio of LAVA was significantly higher than that of T1-fs-Gad (p = 0.0001). The diagnostic efficiency of “T2 + LAVA-Gad” was better than that of “T2 + T1-fs-Gad” (p = 0.0016 for Reader 1, p = 0.0001 for Reader 2) and T2 imaging only (p = 0.0001 for Reader 1; p = 0.0001 for Reader 2). Therefore, LAVA gadolinium-enhanced MR increases the accuracy of diagnosis of LR from rectal cancer and could replace conventional T1 gadolinium-enhanced sequences in the postoperative pelvic follow-up of rectal cancer.

Keywords: Rectal cancer, local recurrence, liver acquisition with acceleration volume acquisition, magnetic resonance imaging

DOI: 10.3233/XST-160594

Journal: Journal of X-Ray Science and Technology, vol. 24, no. 6, pp. 855-863, 2016