Reliability of cone beam CT for morphometry of nasolabial soft tissue in patients with skeletal class III malocclusion: A qualitative and quantitative analysis

Article type: Research Article

Authors: Xu, Wenjie^{a; b; c; 1} | Lu, Rui^{a; b; c; 1} | Hu, Yun^{a; b; c} | Cao, Li^a | Wang, Tao^a | Tan, Hao^{a; b; c} | Meng, Xuehuan^{a; b; c} | Ming, Ye^{a; b; c} | Zheng, Leilei^{a; b; c; *}

Affiliations: [a] Department of Stomatological Hospital of Chongqing Medical University, Chongqing, China | [b] Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences, Chongqing, China | [c] Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Chongqing, China

Correspondence: [*] Corresponding author: Leilei Zheng, DDS, Ph.D., Stomatological Hospital of Chongqing Medical University, No. 426 Songshibei Road, Yubei District, Chongqing 401147, China. E-mail: zhengleileicqmu@hospital.cqmu.edu.cn.

Note: [1] These authors contributed equally to the article.

Abstract: OBJECTIVE: To assess reliability of cone-beam CT (CBCT) for nasolabial soft tissue measurements in patients with skeletal class III malocclusion based on 3-dimensional (3D) facial scanner results. METHODS:CBCT and 3D facial scan images of 20 orthognathic patients are used in this study. Eleven soft tissue landmarks and 15 linear and angular measurements are identified and performed. For qualitative evaluation, Shapiro-Wilk test and Bland-Altman plots are applied to analyze the equivalence of the measurements derived from these two kinds of images. To quantify specific deviation of CBCT measurements from facial scanner, the latter is set as a benchmark, and mean absolute difference (MAD) and relative error magnitude (REM) for each variable are also calculated. RESULTS:Statistically significant differences are observed in regions of nasal base and lower lip vermilion between two methods. MAD value for all length measurements are less than 2 mm and for angular variables < 8°. The average MAD and REM for length measurements are 0.94 mm and 5.64%, and for angular measurements are 2.27° and 3.78%, respectively. CONCLUSIONS:The soft tissue results measured by CBCT show relatively good reliability and can be used for 3D measurement of soft tissue in the nasolabial region clinically.

Keywords: Cone-beam CT, facial scanner, 3-dimensional cephalometry

DOI: 10.3233/XST-211018

Journal: Journal of X-Ray Science and Technology, vol. 30, no. 1, pp. 195-206, 2022