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Article type: Research Article
Authors: Khaled, Alia S.; | Beck, Thomas J.;
Affiliations: Department of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, MD, USA | Division of Medical Imaging Physics, The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, MD, USA | Quantum Medical Metrics, LLC, Baltimore, MD, USA
Note: [] Corresponding author: Alia S. Khaled, Department of Electrical and Computer Engineering, Johns Hopkins University, 3400 N. Charles St, Barton 105, Baltimore, MD 21218, USA. Tel.: +1 443 763 6791; E-mail: akhaled@jhu.edu
Abstract: Relatively high radiation CT techniques are being widely used in diagnostic imaging raising the concerns about cancer risk especially for routine screening of asymptomatic populations. An important strategy for dose reduction is to reduce the number of projections, although doing so with high image quality is technically difficult. We developed an algorithm to reconstruct discrete (limited gray scale) images decomposed into individual tissue types from a small number of projections acquired over a limited view angle. The algorithm was tested using projection simulations from segmented CT scans of different cross sections including mid femur, distal femur and lower leg. It can provide high quality images from as low as 5–7 projections if the skin boundary of the cross section is used as prior information in the reconstruction process, and from 11–13 projections if the skin boundary is unknown.
Keywords: Dual energy X-ray (DXA), image reconstruction, discrete tomography, algebraic reconstruction techniques (ART)
DOI: 10.3233/XST-130363
Journal: Journal of X-Ray Science and Technology, vol. 21, no. 1, pp. 9-24, 2013
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