Affiliations: Department of Plastic Surgery, General Hospital of
Guangzhou Military Command, Guangzhou, China | MOE Key Laboratory of Laser Life Science &
Institute of Laser Life Science, College of Biophotonics, South China Normal
University, Guangzhou, China | Department of Laser Medicine, Chinese PLA General
Hospital, Beijing, China | Plastic Surgery of Nanfang Hospital, Southern Medical
University, Guangzhou, China
Note: [] Corresponding authors: Ying Gu, Professor, Chinese PLA General
Hospital Department of Laser Medicine, Beijing 100853, China. E-mail:
guyinglaser@sina.com. Jianhua Gao, Professor, Southern Medical University,
Plastic Surgery of Nanfang Hospital, Guangzhou 510515, China. E-mail:
gaopsnf@yahoo.com.cn; Da Xing, Professor, South China Normal University, MOE
Key Laboratory of Laser Life Science & Institute of Laser Life Science,
Guangzhou 510631, China. E-mail: xingda@scnu.edu.cn
Abstract: Port wine stains are categorized as a benign capillary vascular
malformation, which is hard to cure. In this paper, a photoacoustic microscopy
system, which integrated a two-dimensional scanning galvanometer, an objective
lens and a focused ultrasound transducer, was designed for noninvasive imaging
of blood vessels of port wine stains model in vivo. Cock comb was chosen
as the port wine stains model in the experiment. The blood vessels in x-y plane
and x-z plane were imaged clearly. Experimental results demonstrate that
photoacoustic microscopy can image the blood vessels of port wine stains model
in vivo with high contrast and high resolution. It has the potential for
clinical applications in detecting the blood vessels in port wine stains skin.
