Affiliations: Biomedical Imaging Division, VT-WFU School of
Biomedical Engineering and Sciences, Virginia Tech, Blacksburg, VA, USA | Department of Physics and Astronomy, University of
North Carolina, Chapel Hill, NC, USA | Department of Radiology, University of North Carolina,
Chapel Hill, NC, USA | VT-WFU School of Biomedical Engineering and Sciences,
Wake Forest University, Winston-Salem, NC, USA | Lineberger Comprehensive Cancer Center, University of
North Carolina, Chapel Hill, NC, USA
Abstract: In the computed tomography (CT) field, one recent invention is the
so-called carbon nanotube (CNT) based field emission x-ray technology. On the
other hand, compressive sampling (CS) based interior tomography is a new
innovation. Combining the strengths of these two novel subjects, we apply the
interior tomography technique to local mouse cardiac imaging using respiration
and cardiac gating with a CNT based micro-CT scanner. The major features of our
method are: (1) it does not need exact prior knowledge inside an ROI;
and (2) two orthogonal scout projections are employed to regularize the
reconstruction. Both numerical simulations and in vivo mouse studies are
performed to demonstrate the feasibility of our methodology.
