Affiliations: Department of Neurology, Stanford University, Stanford, CA, USA
Note: [] Corresponding author: Michelle Monje, M.D., PhD, Stanford
University Department of Neurology, 300 Pasteur Drive, Room A343, Stanford, CA
94305, USA. E-mail: mmonje@stanford.edu
Abstract: Brain tumors and their treatments in children result in a range of
neurological complications that can affect daily function and rehabilitation
potential, including neurocognitive sequelae, ototoxicity, seizure disorders,
stroke, and peripheral neuropathy. Deficits in cognitive function, particularly
learning and memory, attention and speed of information processing, can be
debilitating. With new insights to the cellular and molecular etiology of these
deficits, new therapies for cognitive decline after therapy are emerging.
Management strategies for other neurological complications are also emerging.
Keywords: Brain tumors, late effects, cognition, stroke, neuropathy, seizure
