Affiliations: Seattle Children's Hospital, Seattle, WA, USA
Note: [] Address for correspondence: I. Zamilpa MD, Seattle Children's
Hospital, 4800 Sand Point Way NE, Seattle, WA 98105, USA. E-mail:
ismael.zamilpa@seattlechildrens.org
Abstract: Myelodysplasia is a congenital neural tube defect commonly affecting
bladder and bowel function. Management of fecal incontinence is paramount to
achieve patient independence and self-confidence. When conservative measures
fail alternative invasive methods can be successfully applied. The Malone
antegrade continence enema (MACE) was introduced in the late 1980's to treat
spina bifida patients with fecal incontinence refractory to conservative
management. Since its introduction, multiple successful variations have been
described and its role has expanded. Indeed, the MACE has revolutionized the
care of myelodysplastic patients, their bowel function, and ultimately their
self image.
