Affiliations: Department of Pediatrics, Maulana Azad Medical College
and Associated Lok Nayak Hospital, Delhi, India
Note: [] Correspondence: Devendra Mishra, M.D., Department of Pediatrics,
Maulana Azad Medical College, 2, BSZ Marg, 110002, Delhi, India. Tel.: +91 11
22792421; +91 11 9868604316; Fax: +91 11 23234548; E-mail: drdmishra@gmail.com
Abstract: Valproate associated hyperammonemic encephalopathy is a rare
complication of valproate use, distinct from the more well-known
valproate-induced hepatotoxicity with coma in young children, and the common
finding of asymptomatic hyperammonemia associated with valproate use. We herein
present a 21-month-old child with valproate associated hyperammonemic
encephalopathy and discuss pertinent diagnostic and therapeutic issues for the
pediatrician.
