Affiliations: Department of Child Health (Neurology), Sultan Qaboos
University Hospital, Muscat, Oman
Note: [] Correspondence: Dr. Roshan Koul, MD, DM, FRCPCH, FAAN, Senior
Consultant and Pediatric Neurologist, Department of Child Health (Neurology),
Sultan Qaboos University Hospital, Muscat, Oman. BW-1, P Box 38. E-mail:
roshankoul@hotmail.com
Abstract: Two children with refractory seizures had significant weight loss on
addition of levetiracetam. Despite improved seizure control, we had to withdraw
levetiracetam. Withdrawal of the drug resulted in gradual improvement of
weight. Similar findings were reported in adult patients. Although,
levetiracetam is generally believed not to affect weight, these recent reports
indicate that this drug has the potential of inducing considerable weight loss
in both adults and children. Parents need to be warned about this potential
side effect.
