Affiliations: Department of Neuroradiology, Hospital Pedro Hispano,
Matosinhos, Portugal | Department of Neurology, Hospital Pedro Hispano,
Matosinhos, Portugal
Note: [] Correspondence: Dr. Mavilde Arantes, M.D., Department of
Neuroradiology, Hospital Pedro Hispano, 4464-513, Matosinhos, Portugal. Tel.:
+351 229391000; Fax: +351 229391654; E-mail: mavildearantes@hotmail.com
Abstract: Schizencephaly is an uncommon disorder of cell migration
characterized by communication clefts between ventricular system and
subarachnoid space. The clefts may be unilateral or bilateral and may be closed
or separated. Patients with bilateral clefts typically present with severe
mental deficits, motor anomalies and seizures. We report a 16-year-old girl
whose cranial magnetic resonance imaging revealed bilateral open-lip
schizencephaly, but with an atypical clinical course. She had minimally
recognizable neurological deficits and epilepsy for last one year. Such mild
clinical phenotypes were not proportional to the magnetic resonance imaging of
the cerebral malformation.
Keywords: Migration disorder, schizencephaly, magnetic resonance image
