Affiliations: Department of Pediatrics, Sapporo Medical University
School of Medicine, Sapporo, Japan | Hokkaido Medical Center for Child Health and
Rehabilitation, Sapporo, Japan
Note: [] Correspondence: Masaki Yamamoto, Department of Pediatrics,
Sapporo Medical, University School of Medicine, S1W16 Chuo-ku, Sapporo,
060-8543, Japan. Tel.: + 81 11 611 2111 (ext. 3413); Fax: +81 11 611 0352;
E-mail: ymasaki@sapmed.ac.jp
Abstract: Fungal arthritis is a relatively rare complication, which occurs in
patients with hematological disease and cancer. Recently non-albicans Candida
species have emerged as clinically important agents; however, Candida krusei
(C. krusei) arthritis is still rare. We report a 6-year-old boy who developed
C. krusei arthritis associated with acute lymphoblastic leukemia. He was given
oral fluconazole and broad-spectrum antibiotics prophylactically, but
nevertheless, he developed fungemia with C. krusei and subsequently developed
arthritis in his right hip. He was successfully treated with liposomal
amphotericin B and micafungin combined with surgical drainage. This is the
youngest case with C. krusei arthritis.
