Affiliations: Neonatal Paediatrics, Child and Adolescent Health
Service, Perth, Australia | Department of Paediatrics and Adolescent Medicine,
Princess Margaret Hospital for Children, Perth, Australia | School of Paediatrics and Child Health, University of
Western Australia, Perth, Australia | Murdoch Childrens Research Institute, Royal Children's
Hospital, Parkville, Australia
Note: [] Correspondence: David Burgner, Murdoch Childrens Research
Institute, Royal Children's Hospital, Flemington Road, Parkville, Victoria
3052, Australia. Tel.: +613 9936 6530; Fax: +613 9936 6528; E-mail:
david.burgner@mcri.edu.au
Abstract: Kawasaki disease (KD) is rare in neonates, who have fewer cardinal
diagnostic features, potentially contributing to delayed diagnosis and worse
outcome. We describe two infants who developed features consistent with
incomplete KD in the first three weeks of life, who are amongst the youngest
ever reported. The suggestive clinical features and lack of alternative
aetiology prompted treatment of KD, with excellent response and no coronary
artery sequelae. Current diagnostic guidelines are recognized to be relatively
insensitive in infants. KD should be considered in infants with prolonged
fever, irrespective of other clinical features.
