Affiliations: Department of Clinical Microbiology, University
Hospital Split and School of Medicine, University of Split, Split,
Croatia | Department of Pediatrics, University Hospital Split
and School of Medicine, University of Split, Split, Croatia | Department of Infectious Diseases, University Hospital
Split, Split, Croatia | Department of Diagnostic and Interventional Radiology,
University Hospital Split and School of Medicine, University of Split, Split,
Croatia
Note: [] Correspondence: Ivana Goić-Barišić M.D., Department of
Clinical Microbiology, University Hospital Split, Spinciceva 1, 21000 Split,
Croatia. Tel.: +1 385 21 556201; E-mail: ivanagoicbar@net.hr
Abstract: Tuberculous meningitis is the most serious form of tuberculosis and
carries a high mortality and morbidity despite the availability of effective
chemotherapeutic agents. Poor response to therapy or death is often due to
failure to begin appropriate therapy in the early stages of the disease. We
report a rare case of tuberculous meningitis in a 7-month old infant following
unsuccessful vaccination and close exposure to adult uncle who died from
pulmonary tuberculosis when she was 3 months old. The described case points out
serious possibility of pulmonary tuberculosis with meningitis in non-vaccinated
or unsuccessfully vaccinated children and importance of the chemoprophylaxis in
infants who were exposed to tuberculous infection, as well as early discovery
and treatment of illness.
