Affiliations: [a] Department of Neonatology, PGIMER and Dr. RML Hospital, New Delhi, India
| [b] Department of Neonatology, Lady Hardinge Medical College, New Delhi, India
| [c] Department of Pediatrics, Division of Pediatric Cardiology, PGIMER and Dr. RML Hospital, New Delhi, India
Correspondence:
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Address for correspondence: Tapas Bandyopadhyay, DM (Neonatology), Department of Neonatology, PGIMER and Dr. RML Hospital, New Delhi, India. Tel.: +91 9910371315; E-mail: dr.tapasbanerjee@gmail.com.
Abstract: BACKGROUND:To evaluate the correlation between functional echocardiography and clinical parameters in term neonates with shock. METHOD:Cross sectional study of 30 full term newborns who were clinically detected to have shock compared to 30 full term hemodynamically stable neonates. For statistical analysis, cases were further sub classified into cardiogenic and septic shock. RESULT:Functional echocardiography revealed inferior vena cava collapsibility index (cIVC), fractional shortening (FS), ejection fraction (EF), cardiac output and superior vena cava (SVC) flow were significantly lower whereas myocardial performance index (MPI) was significantly higher in babies with cardiogenic and septic shock as compared to the controls. Left ventricular end diastolic area (LVEDA) was significantly higher in cardiogenic shock whereas it was significantly lower in septic shock as compared to the controls. Also, cIVC was significantly lower and LVEDA was significantly higher in cardiogenic as compared to the septic shock. In cardiogenic shock SVC flow correlated significantly with capillary filling time and systolic blood pressure. The correlation between functional echocardiographic parameters of cardiogenic and septic shock showed that EF, FS and MPI were positively and significantly correlated (r 0.742, p 0.022 for EF, r 0.766, p 0.016 for FS and r 0.478, p 0.05 for MPI) whereas SVC flow and cIVC were negatively and significantly correlated between cardiogenic and septic shock (r – 0.655, p 0.045 for SVC flow and – 0.578, p 0.05 for cIVC). CONCLUSION:In the complex environment of neonatal intensive care unit detection of shock continues to be a major challenge. Functional echocardiography provides an adjunct information to the clinical assessment of shock and helps in monitoring the response to treatment.
Keywords: Functional echocardiography, shock, BP, IVC, SVC, neonatal intensive
care unit, correlation, IVC collapsibility index
