Affiliations: [a] Department of Basic Medical Science, College of Medicine, Majmaah University, Al-Majmaah, Riyadh, Saudi Arabia
| [b] Department of Anaesthesia, Faculty of Dentistry, Jamia Millia Islamia, Jamia Nagar, New Delhi, Delhi, India
| [c] Pediatric and Preventive Dentistry, Yenepoya Dental College, Mangalore, India
| [d] Department of Prosthodontics and Crown and Bridge, AB Shetty Memorial institute of Dental Sciences, Nitte deemed to be University, Mangalore, India
| [e] Department of Periodontology Rural Dental College, Loni, Maharashtra, India
Correspondence:
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Corresponding author: Dr. Preeti Prakash Kale, Assistant Professor, Department of Periodontology. Rural Dental College and Hospital, Loni, India. E-mail: preetikale20jan@gmail.com.
Abstract: Molecular dentistry, propelled by advancements in techniques such as Polymerase Chain Reaction (PCR), has emerged as a promising frontier in dental research and practice. PCR has revolutionized the field of dentistry by enabling precise and sensitive detection of various oral pathogens, genetic markers associated with dental diseases, and host response factors. Its ability to amplify specific DNA sequences from minimal starting material has facilitated rapid and accurate diagnosis of dental infections, periodontal diseases, and genetic predispositions to oral conditions. Moreover, PCR-based methods have enhanced our understanding of the oral microbiome composition and its relationship with overall health. This review article aims to elucidate the transformative role of PCR in molecular dentistry by providing an overview of its applications, current developments, and future prospects.
